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ATF6B antibody

ATF6B antibody

ArtNr	FNab00665-100ug
Hersteller	FineTest
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IF, IP, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Purity	≥95% as determined by SDS-PAGE
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Cyclic AMP-dependent transcription factor ATF-6 beta (cAMP-dependent transcription factor ATF-6 beta),Activating transcription factor 6 beta (ATF6-beta),Protein G13,cAMP response element-binding protein-related protein (Creb-rp),cAMP-responsive element-binding protein-like 1,Processed cyclic AMP-dependent transcription factor ATF-6 beta,ATF6B,CREBL1,G13
Lieferbar
Manufacturer - Targets	ATF6B
Storage Conditions	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Background	The endoplasmic reticulum (ER)-transmembrane proteins, ATF6 alpha (ATF6) and ATF6 beta (ATF6B), are cleaved during the ER stress response (ERSR). The resulting N-terminal fragments of both ATF6 isoforms, which have conserved basic leucine-zipper and DNA binding domains but divergent transcriptional activation domains, translocate to the nucleus where they bind to ER stress-response elements (ERSE) in ERSR, such as Bip/GRP78. This antibody could recognize ATF6 beta (110kd) and its cleaved forms(60, 80kd )(PMID: 11256944)
Clonality	polyclonal
Immunogen	activating transcription factor 6 beta
Observed MW	110 kDa, 60 kDa, 80 kDa
Purification	Immunogen affinity purified
Recommended dilution	WB: 1:1000-1:4000; IP:1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Manufacturer - Research Area	Signal Transduction, Metabolism
Manufacturer - Synonym	Cyclic AMP-dependent transcription factor ATF-6 beta (cAMP-dependent transcription factor ATF-6 beta), Activating transcription factor 6 beta (ATF6-beta), Protein G13, cAMP response element-binding protein-related protein (Creb-rp), cAMP-responsive element-binding protein-like 1, Processed cyclic AMP-dependent transcription factor ATF-6 beta, ATF6B, CREBL1, G13

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