Item no. |
FNab00665-100ug |
Manufacturer |
FineTest
|
Amount |
100 ug |
Category |
|
Type |
Antibody Monoclonal |
Format |
Liquid |
Applications |
WB, IF, IP, IHC, ELISA |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus) |
Host |
Rabbit |
Isotype |
IgG |
Purity |
≥95% as determined by SDS-PAGE |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Cyclic AMP-dependent transcription factor ATF-6 beta (cAMP-dependent transcription factor ATF-6 beta),Activating transcription factor 6 beta (ATF6-beta),Protein G13,cAMP response element-binding protein-related protein (Creb-rp),cAMP-responsive element-binding protein-like 1,Processed cyclic AMP-dependent transcription factor ATF-6 beta,ATF6B,CREBL1,G13 |
Available |
|
Manufacturer - Targets |
ATF6B |
Storage Conditions |
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.) |
Background |
The endoplasmic reticulum (ER)-transmembrane proteins, ATF6 alpha (ATF6) and ATF6 beta (ATF6B), are cleaved during the ER stress response (ERSR). The resulting N-terminal fragments of both ATF6 isoforms, which have conserved basic leucine-zipper and DNA binding domains but divergent transcriptional activation domains, translocate to the nucleus where they bind to ER stress-response elements (ERSE) in ERSR, such as Bip/GRP78. This antibody could recognize ATF6 beta (110kd) and its cleaved forms(60, 80kd )(PMID: 11256944) |
Clonality |
polyclonal |
Immunogen |
activating transcription factor 6 beta |
Observed MW |
110 kDa, 60 kDa, 80 kDa |
Purification |
Immunogen affinity purified |
Recommended dilution |
WB: 1:1000-1:4000; IP:1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100 |
Manufacturer - Research Area |
Signal Transduction, Metabolism |
Manufacturer - Synonym |
Cyclic AMP-dependent transcription factor ATF-6 beta (cAMP-dependent transcription factor ATF-6 beta), Activating transcription factor 6 beta (ATF6-beta), Protein G13, cAMP response element-binding protein-related protein (Creb-rp), cAMP-responsive element-binding protein-like 1, Processed cyclic AMP-dependent transcription factor ATF-6 beta, ATF6B, CREBL1, G13 |
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