Comparison

ATF6B antibody

Item no. FNab00665-100ug
Manufacturer FineTest
Amount 100 ug
Category
Type Antibody Monoclonal
Format Liquid
Applications WB, IF, IP, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Purity ≥95% as determined by SDS-PAGE
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Cyclic AMP-dependent transcription factor ATF-6 beta (cAMP-dependent transcription factor ATF-6 beta),Activating transcription factor 6 beta (ATF6-beta),Protein G13,cAMP response element-binding protein-related protein (Creb-rp),cAMP-responsive element-binding protein-like 1,Processed cyclic AMP-dependent transcription factor ATF-6 beta,ATF6B,CREBL1,G13
Available
Manufacturer - Targets
ATF6B
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Background
The endoplasmic reticulum (ER)-transmembrane proteins, ATF6 alpha (ATF6) and ATF6 beta (ATF6B), are cleaved during the ER stress response (ERSR). The resulting N-terminal fragments of both ATF6 isoforms, which have conserved basic leucine-zipper and DNA binding domains but divergent transcriptional activation domains, translocate to the nucleus where they bind to ER stress-response elements (ERSE) in ERSR, such as Bip/GRP78. This antibody could recognize ATF6 beta (110kd) and its cleaved forms(60, 80kd )(PMID: 11256944)
Clonality
polyclonal
Immunogen
activating transcription factor 6 beta
Observed MW
110 kDa, 60 kDa, 80 kDa
Purification
Immunogen affinity purified
Recommended dilution
WB: 1:1000-1:4000; IP:1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Manufacturer - Research Area
Signal Transduction, Metabolism
Manufacturer - Synonym
Cyclic AMP-dependent transcription factor ATF-6 beta (cAMP-dependent transcription factor ATF-6 beta), Activating transcription factor 6 beta (ATF6-beta), Protein G13, cAMP response element-binding protein-related protein (Creb-rp), cAMP-responsive element-binding protein-like 1, Processed cyclic AMP-dependent transcription factor ATF-6 beta, ATF6B, CREBL1, G13

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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