ATP8A1 antibody

ArtNr	FNab00728-100ug
Hersteller	FineTest
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Purity	≥95% as determined by SDS-PAGE
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Phospholipid-transporting ATPase IA,ATPase class I type 8A member 1,Chromaffin granule ATPase II,P4-ATPase flippase complex alpha subunit ATP8A1,ATP8A1,ATPIA
Lieferbar
Manufacturer - Targets	ATP8A1
Storage Conditions	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine(PS). The flippase complex ATP8A1:TMEM30A seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine(PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells.
Clonality	polyclonal
Immunogen	ATPase, aminophospholipid transporter(APLT), class I, type 8A, member 1
Observed MW	120 kDa
Purification	Immunogen affinity purified
Recommended dilution	WB: 1:500-1:2000
Manufacturer - Research Area	Metabolism

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