NRCAM antibody

ArtNr	FNab05852-100ug
Hersteller	FineTest
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Purity	≥95% as determined by SDS-PAGE
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Neuronal cell adhesion molecule (Nr-CAM),Neuronal surface protein Bravo (hBravo),NgCAM-related cell adhesion molecule (Ng-CAM-related),NRCAM,KIAA0343
Lieferbar
Manufacturer - Targets	NRCAM
Storage Conditions	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons. Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters. Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier.
Clonality	polyclonal
Immunogen	neuronal cell adhesion molecule
Observed MW	130-136 kDa
Purification	Immunogen affinity purified
Recommended dilution	WB: 1:500-1:2000; IHC: 1:20-1:200
Manufacturer - Research Area	Immunology, Cardiovascular, Developmental biology, Signal Transduction

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