anti- TRPV5 antibody

ArtNr	FNab09029-100ug
Hersteller	FineTest
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	IF, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Purity	>=95% as determined by SDS-PAGE
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Calcium transport protein 2,CAT2,ECaC,ECAC1,Epithelial calcium channel 1,Osm 9 like TRP channel 3,OTRPC3,TRPV5
Lieferbar
Storage Conditions	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20C for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine(PubMed:11549322, PubMed:18768590). Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules(By similarity). The channel is activated by low internal calcium level and the current exhibits an inward rectification(PubMed:11549322, PubMed:18768590). A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay(By similarity). Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating(By similarity).
Clonality	polyclonal
Immunogen	transient receptor potential cation channel, subfamily V, member 5
Observed MW	43 kDa
Purification	Immunogen affinity purified
Recommended dilution	IF: 1:10-1:100
Manufacturer - Research Area	Epigenetics, Metabolism

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