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Bulk Anti-Human CD8 (UCHT-4) Antibody

Bulk Anti-Human CD8 (UCHT-4) Antibody

ArtNr	ICH1005-5MG
Hersteller	IchorBio
Menge	5 mg
Quantity options	100 mg 1 mg 25 mg 50 mg 5 mg
Kategorie	Oncology Antibodies In Vivo Antibodies By Cell Type Hematology Leukemia Flow Cytometry Western Blot
Typ	Antibody
Applikationen	WB, FC, IF, IP, IHC, ELISA, FA
Clon	UCHT-4
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a
Purity	>95% by SDS-PAGE and HPLC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	in vivo
Versandbedingung	Gekühlt
Lieferbar
Specificity	Anti-CD8 In Vivo Antibody - Low Endotoxin (UCHT-4) recognizes Human CD8. Anti-Human CD8 recognizes a T-cell glycoprotein cell surface complex (Mr 32 kDa) which defines the cytotoxic/suppressor population of mature T-lymphocytes. The CD8 complex interacts
Manufacturer - Applications	Flow Cytometry, Western Blot, Immunoprecipitation, Functional Assays, IHC, Immunofluorescence, ELISA
Manufacturer - Category	Low Endotoxin, anti-human, monoclonal antibody
Manufacturer - Isotype	Mouse IgG2a
Manufacturer - Targets	CD8
Shipping Temperature	Blue ice
Storage Conditions	anti-CD8 In Vivo Antibody - Low Endotoxin (UCHT-4) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Aggregation	Aggregation level ≤ 5%
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution	The CD8 antigen is expressed on approximately 19-48% of normal human peripheral blood lymphocytes and > 90% of normal thymocytes. It is also present on a subset of NK cells. Subjects infected with HIV have been shown to exhibit increased levels of CD8+ lymphocytes with a continual decrease in CD4+ lymphocytes.
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Background	Anti-CD8 may be used in studies of immunoregulation and T-lymphocyte mediated suppression, autoimmune disorders, immunodeficiency states and acute lymphoblastic leukemia and lymphoma.
Concentration	1.0 - 5.0 mg/ml
Endotoxin	<1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity	Anti-CD8 In Vivo Antibody - Low Endotoxin (UCHT-4) recognizes Human CD8. Anti-Human CD8 recognizes a T-cell glycoprotein cell surface complex (Mr 32 kDa) which defines the cytotoxic/suppressor population of mature T-lymphocytes. The CD8 complex interacts with class I MHC molecules resulting in increased adhesion between CD8+ T-lymphocytes and their target cells. Binding of the CD8 antigen to Class I MHC molecules enhances T-cell activation. The cytoplasmic portion of the CD8 antigen is associated with a protein tyrosine kinase (p56lck).
Purification method	This monoclonal antibody was purified using Protein A
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Antibodies against the same target (Cat No.)	ICH1043-100MG, AICH1043UL-100MG
Isotype Control	Mouse IgG2a In Vivo Isotype Control - Low Endotoxin [C1.18.4] (ICH2245)
Buffer	ICH3001-100ml; ICH3002-100ml; ICH3003-100ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ICH1005-5MG-datasheet.pdf

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Menge: 5 mg

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Lieferung vsl. bis 05.06.2025

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