Hersteller |
IchorBio
|
Kategorie |
|
Typ |
Antibody |
Specific against |
Mouse |
Clon |
GL1 |
Isotype |
IgG2a Kappa |
Applikationen |
WB, Blocking |
Menge |
1mg |
Host |
Rat |
ArtNr |
ICH1038-1MG |
Targets |
CD86 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Aggregation |
Aggregation level <= 5% |
Antigen Distribution |
B cells and T cells (upregulated upon activation), macrophages, dendritic cells, and astrocytes |
Application Notes |
Each investigator should determine their own optimal working dilution for specific applications. |
Background |
CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the Ig gene superfamily. CD86 is a ligand for CD28 and CD152 (CTLA-4). CD86 is related to the CD80 molecule and functions as a counterreceptor for CD28 and CTLA-4. The GL1 clone has been shown to provide critical signals for T-Cell-dependent responses in vivo and in vitro. |
Concentration |
1.0 mg/ml |
Endotoxin |
<= 1.0 EU/mg as determined by the LAL method |
Formulation |
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
Immunogen |
LPS-activated CBA/Ca mouse splenic B cells |
Product Type |
Low Endotoxin, anti-mouse |
Purification method |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
Storage |
anti-CD86 In Vivo Antibody - Low Endotoxin (GL1) is stable when stored at 2-8C. For long term storage aseptically aliquot in working volumes without diluting and store at -80C. Avoid Repeated Freeze Thaw Cycles. |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.