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Anti-Mouse CD86 In Vivo Antibody - Low Endotoxin (GL1)

Anti-Mouse CD86 In Vivo Antibody - Low Endotoxin (GL1)

Manufacturer	IchorBio
Category	Antibodies In Vivo Antibodies Western Blot Blocking
Type	Antibody
Specific against	Mouse
Clone	GL1
Isotype	IgG2a Kappa
Applications	WB, Blocking
Amount	1mg
Host	Rat
Item no.	ICH1038-1MG
Targets	CD86
eClass 6.1	32160702
eClass 9.0	32160702
Available
Aggregation	Aggregation level <= 5%
Antigen Distribution	B cells and T cells (upregulated upon activation), macrophages, dendritic cells, and astrocytes
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Background	CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the Ig gene superfamily. CD86 is a ligand for CD28 and CD152 (CTLA-4). CD86 is related to the CD80 molecule and functions as a counterreceptor for CD28 and CTLA-4. The GL1 clone has been shown to provide critical signals for T-Cell-dependent responses in vivo and in vitro.
Concentration	1.0 mg/ml
Endotoxin	<= 1.0 EU/mg as determined by the LAL method
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Immunogen	LPS-activated CBA/Ca mouse splenic B cells
Product Type	Low Endotoxin, anti-mouse
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Storage	anti-CD86 In Vivo Antibody - Low Endotoxin (GL1) is stable when stored at 2-8C. For long term storage aseptically aliquot in working volumes without diluting and store at -80C. Avoid Repeated Freeze Thaw Cycles.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1mg

available

Delivery expected until 6/6/2024