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Anti-Mouse IL-4 In Vivo Antibody - Low Endotoxin (11B11) Europäischer Partner

Hersteller IchorBio
Kategorie
Typ Antibody
Specific against Mouse
Clon 11B11
Isotype IgG1 Kappa
Applikationen FC, ELISA
Menge 0.5mg
Host Rat
ArtNr ICH1087-0.5MG
Targets IL4
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Aggregation
Aggregation level <= 5%
Application Notes
ELISA Sandwich: This antibody is useful as the capture antibody in a sandwich ELISA. The suggested coating concentration is 0.5-2.0 ug/ml. ELISPOT Capture: This Low Endotoxin Functional Formulation antibody has been reported for use as the capture antibody in a sandwich ELISPOT assay. Aseptically coat plates at a concentration of 2-6 ug/ml is recommended. Neutralization: Anti-Mouse IL-4 (clone 11B11) antibody can neutralize the bioactivity of natural or recombinant IL-4. The Low Endotoxin Functional Formulation purified antibody (Endotoxin <0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for neutralization of mouse IL-4 bioactivity in vivo. Each investigator should determine their own optimal working dilution for specific applications.
Background
Interleukin-4 (IL-4) is a pleiotropic immune cytokine secreted by activated TH2 cells that inhibits bone resorption. IL-4 is critical for inducing allergic responses. It has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is also a key regulator in humoral and adaptive immunity. IL-4 is required for the pathogenesis of atopic diseases and immune regulation.
Concentration
1.0 - 5.0 mg/ml
Endotoxin
<0.5 EU/mg as determined by the LAL method
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Immunogen
Purified Recombinant Mouse IL-4 (>98%)
Product Type
Low Endotoxin, anti-mouse
Purification method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Storage
anti-IL-4 In Vivo Antibody - Low Endotoxin (11B11) is stable when stored at 2-8C for 1 week. For long term storage aseptically aliquot in working volumes without diluting and store at -80C. Avoid Repeated Freeze Thaw Cycles.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.5mg
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 06.06.2024 

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