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Antibodies

Anti-Mouse TCR V gamma 2 In Vivo Antibody - Low Endotoxin (UC3-10A6) Europäischer Partner

Hersteller IchorBio
Kategorie
Typ Antibody
Specific against Mouse
Clon UC3-10A6
Isotype IgG
Applikationen FC, IP, IV
Menge 5mg
Host Hamster - Armenian
ArtNr ICH1140-5MG
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Manufacturers Product Category
Low Endotoxin, anti-mouse
Target Information
TCR V gamma 2
Isotype Information
Armenian Hamster IgG
Purification method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution
V gamma 2 T-Cell Receptor (TCR)-bearing T lymphocytes make up a significant proportion of gamma delta TCR-bearing cells in the late fetal and adult thymus and adult peripheral lymphoid tissues and lung.
Background
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an alpha and beta chain in 95% of T cells, while 5% of T cells have TCRs consisting of gamma and delta chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
Concentration
1.0 - 5.0 mg/ml
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Endotoxin
<1.0 EU/mg as determined by the LAL method
Aggregation
Aggregation level ≤ 5%
Storage
anti-TCR V gamma 2 In Vivo Antibody - Low Endotoxin (UC3-10A6) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Application Notes
Flow Cytometry: It is recommended to use the indirect method for signal enhancement when enumerating cells expressing TCR. A suggested method would be to stain cells expressing TCR with Anti-Mouse TCR at ≤1.0 µg per 1.0 X 106 cells in a 100 µl total staining volume, followed by Goat Goat Anti-Armenian Hamster IgG (H&L)-R-phycoerythrin - Each investigator should determine their own optimal working dilution for specific applications.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 5mg
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 06.06.2024 

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