Anti-Mouse CD25 - Purified - 500 µg

B, Depletion, FA, FC, IHC FF, IP, WB

CD25

Next Day Ambient

CD25, a 55 kD type I transmembrane glycoprotein, has been shown to play roles in lymphocyte differentiation, activation, and proliferation. Many resting memory T cells constitutively express IL2RA. It functions as the receptor for HTLV-1, resulting in its expression on neoplastic cells in adult T cell lymphoma/leukemia. CD25 (sIL-2R) has been used to track disease progression. Some additional clinical applications include Chagas disease, a disease characterized by a decline of CD25 expression on immune cells, and Multiple sclerosis, in which treatments with mAbs target CD25.

CODEX®
B
Depletion
IHC (Frozen)
IP
FA

IL-2

Clone PC61 recognizes an epitope on mouse CD25.

0.5 mg/ml

CD25 is expressed in activated T cells and B cells, thymocyte subset, pre-B cells, T regulatory cells.

Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.