Anti-Human CXCL1 (Clone 20326) - 25 µg

CyTOF®, ELISA Cap, FC, N, WB

CXCL1

Next Day Ambient

Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine with mitogenic properties belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROα, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-α).1 CXCL1 is expressed by macrophages, neutrophils and epithelial cells.2 CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing.3, 4

Neutralization: This antibody is useful for neutralization of Human CXCL1 bioactivity. The antibody dose required to neutralize 50% (ND₅₀) of the biological activity of Human CXCL1 (at 10 ng/ml) is 3-15 µg/ml.
CyTOF-ready: Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Chemokine

AB_2828450

< 0.1 EU/µg as determined by the LAL method

Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.