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Anti-Human ILPIP (Intermediate Domain) - 0.1 mg

Anti-Human ILPIP (Intermediate Domain) - 0.1 mg

ArtNr	LEIN-I-489-0.1mg
Hersteller	Leinco Technologies
Menge	0.1 mg
Quantity options	0.1 mg 20 ug
Kategorie	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Primary
Applikationen	WB, IHC
Specific against	Human (Homo sapiens)
Host	Rabbit
Citations	1. Sanna, MG. et al. (2002) J Biol Chem. 277(34):30454-62. 2. Sanna, MG. et al. (1998) Proc Natl Acad Sci U S A. 95(11):6015-20. 3. Nishigaki, K. et al. (2003) J Biol Chem. 278(15):13520-30.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Applications	IHC FFPE, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Apoptosis & Cell Biology
Manufacturer - Targets	ILPIP
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Product Description	ILPIP (ILP-interacting protein) has recently been shown to interact with XIAP, a member of the IAP (Inhibitor of Apoptosis) protein family.1 Together, these two proteins synergistically activate the TAK1/JNK1 signal transduction pathway, which acts to protect against the interleukin-1 converting enzyme of Fas-induced apotosis.1, 2 This protein was independently isolated and characterized as polyploidy-associated protein kinase (PAPK), a member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival, 3 suggesting that its protective role may be a function of its kinase activity. Although two mRNA sequences have been isolated, only the shorter isoform has been observed.
Background	ILPIP (ILP-interacting protein) has recently been shown to interact with XIAP, a member of the IAP (Inhibitor of Apoptosis) protein family.¹ Together, these two proteins synergistically activate the TAK1/JNK1 signal transduction pathway, which acts to protect against the interleukin-1 converting enzyme of Fas-induced apotosis.^{1, 2} This protein was independently isolated and characterized as polyploidy-associated protein kinase (PAPK), a member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival, ³ suggesting that its protective role may be a function of its kinase activity. Although two mRNA sequences have been isolated, only the shorter isoform has been observed.
PubMed	ILPIP
Manufacturer - Specificity	Rabbit Anti-Human ILPIP recognizes mouse, rat and human ILPIP. This polyclonal antibody was purified using affinity chromatography.
RRID	AB_2830707
Concentration	0.5 mg/ml
Formulation	This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Immunogen	PN:I-496
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Polyclonal Antibody, ILP-Interacting Protein, ILP-Interacting Protein, ILPIP, Human, Anti-Human ILPIP (Intermediate Domain), ILPIP Antibody, PAPK, ILPIP, ILPIPA, ALS2CR2, CALS-21, PRO1038, STE20-related kinase adapter protein beta, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein, STRAD beta

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LEIN-I-489-0.1mg-safety-datasheet.pdf