Anti-Human PD-ECGF - 100 µg

IHC FFPE, N, WB

PD-ECGF

Next Day Ambient

Platelet-Derived Endothelial Cell Growth Factor (PD-ECGF) is an acidic non-glycosylated protein found in connective tissue of the placenta. It is synthesized by fibroblasts, vascular smooth muscle cells, and a number of transformed cell lines.1 PDGF promotes the proliferation and migration of pulmonary artery smooth muscle cells (PASMCs), and may play a role in the progression of pulmonary arterial hypertension (PAH), a condition characterized by proliferation of PASMCs resulting in the obstruction of small pulmonary arteries.2

IHC (NBF/Par.): This antibody should give satisfactory staining results when used at a concentration of 5-15 µg/ml. The recommended secondary antibody for IHC is PN:G505. For chromogenic detection with high signal and low background use PN:D100 or PN:K107.
Neutralization: This antibody is useful for neutralization of Human PD-ECGF bioactivity. The antibody dose required to neutralize 50% (ND₅₀) of the biological activity of Human PD-ECGF (at 150 ng/ml) is 0.5-2.0 µg/ml.

Goat Anti-Human Platelet-Derived Endothelial Cell Growth Factor (PD-ECGF) recognizes Human PD-ECGF. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.

This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.

Sf21-derived human PD-ECGF

Polyclonal Antibody, PD-ECGF, Endothelial Cell Growth Factor-1 ECGF-1, Gliostatin, Platelet-Derived Endothelial Cell Migration, PD-ECGF, Human PD-ECGF, Anti-Human PD-ECGF, dThdPase, EC 2.4.2, EC 2.4.2.4, ECGF, ECGF1, ECGF1TP, endothelial cell growth factor 1 platelet-derived, Gliostatin, hPD-ECGF, MEDPS1, MNGIE, MTDPS1, PDECGF, PD-ECGF, Platelet-derived endothelial cell growth factor, TdRPase, Thymidine Phosphorylase, TPase, TYMP