WWOX Antibody

ArtNr	PRS-14-562-50uL
Hersteller	ProSci
Menge	50 uL
Quantity options	100 uL
Kategorie	Antibodies Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	WWOX
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	WW domain-containing oxidoreductase, 111-, Fragile site FRA16D oxidoreductase, WWOX, FOR, WOX1
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Manufacturer - Applications	WB: 1:1000 - 1:2000 IF: 1:50 - 1:200
Shipping Temperature	blue ice or room temperature
Storage Conditions	Store at -20°C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 46kDa
Manufacturer - Research Area	Apoptosis, Cancer, Cell Cycle, Growth Factors, Neuroscience
Background	This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.
Purification	Affinity purification
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human WWOX (NP_057457.1).
Clonality	Polyclonal
NCBI Official Name	WW domain-containing oxidoreductase
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Menge: 50 uL

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