Vergleich

EIF5B Antibody

ArtNr PRS-15-888-50uL
Hersteller ProSci
Menge 50 uL
Quantity options 100 uL
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
NCBI EIF5B
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias IF2, eukaryotic translation initiation factor 5B, eIF-5B, translation initiation factor IF-2, translation initiation factor IF2
Lieferbar
Manufacturer - Applications
WB: 1:500 - 1:2000
Shipping Temperature
blue ice or room temperature
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Molecular Weight
Observed: 179kDa
Manufacturer - Research Area
Other
Background
Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately.
Purification
Affinity purification
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-273 of human EIF5B (NP_056988.3).
Clonality
Polyclonal
NCBI Official Name
eukaryotic translation initiation factor 5B
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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