CD151 Antibody

Cell Cycle, Immunology, Signal Transduction

WB: 1:500 - 1:2000

IHC: 1:50 - 1:200

Observed: 28kDa

Polyclonal

Unconjugated

Store at -20˚ C. Avoid freeze / thaw cycles.

None

977

CD151

Homo sapiens

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.

Immunohistochemistry of paraffin-embedded rat kidney using CD151 antibody (18-393) at dilution of 1:200 (40x lens).