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CD151 Antibody

CD151 Antibody

Manufacturer	ProSci
Category	Neuroscience Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Antibodies Obesity Immunohistochemistry Western Blot Primary Antibodies Other Lipid\Cholesterol Metabolism Modulators
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Format	Liquid
Applications	WB, IHC
Amount	50 uL
Host	Rabbit
Item no.	PRS-18-393-50uL
eClass 6.1	32160702
eClass 9.0	32160702
Available
Shipping	blue ice or RT
By Research Area	Cell Cycle, Immunology, Signal Transduction
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 113-221 of human CD151 (NP_001034579.1).
Applications	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200
Positive Control 1	Mouse skeletal muscle
Predicted Molecular Weight	Observed: 28kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	CD151
Ncbi Gene Id #	977
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	CD151
Ncbi Official Full Name	CD151 molecule (Raph blood group)
Ncbi Organism	Homo sapiens
Swissprot #	P48509
Background	The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.
1st Image Caption	Western blot analysis of extracts of mouse skeletal muscle, using CD151 Antibody (18-393) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit.
2nd Image Caption	Immunohistochemistry of paraffin-embedded rat kidney using CD151 antibody (18-393) at dilution of 1:200 (40x lens).
3rd Image Caption	Immunohistochemistry of paraffin-embedded human lung cancer using CD151 antibody (18-393) at dilution of 1:200 (40x lens).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 uL

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Delivery expected until 6/6/2024