DNase II Antibody

Blue Ice

Aprox: 40 kDa

DNase II Antibody: Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins including AIF and Acinus. DNase II causes both chromatin condensation and DNA fragmentation. The genes encoding human, porcine, and murine DNase II have been cloned. The DNase II gene encodes a 40 kDa proenzyme. The mature enzyme consists of two non-identical subunits, the 32 kDa (alpha) and 12 kDa (beta) chains, generated by proteolytic processing. Overexpression of DNase II induces chromatin condensation. DNase II is ubiquitously expressed in human tissues.

Trial Size

2921838

PRS-1306-0.1mg

PRS-10-901-4um

DNase II Antibody is supplied in PBS containing 0.02% sodium azide.

DNase II antibody was raised against a 14 amino acid peptide near the carboxy terminus of human DNase II.

The immunogen is located within the last 50 amino acids of DNase II.

deoxyribonuclease II, lysosomal

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.