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PTPRN2 Antibody

ArtNr PRS-58-680-400ul
Hersteller ProSci
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
NCBI PTPRN2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Receptor-type tyrosine-protein phosphatase N2, R-PTP-N2, Islet cell autoantigen-related protein, IAR, ICAAR, Phogrin, PTPRN2, KIAA0387
Lieferbar
Manufacturer - Applications
For WB starting dilution is: 1:1000
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
blue ice or room temperature
Storage Conditions
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
111 kDa
Manufacturer - Research Area
Immunology, Signal Transduction
Background
The protein encoded by this gene is a member of theprotein tyrosine phosphatase (PTP) family. PTPs are known to besignaling molecules that regulate a variety of cellular processesincluding cell growth, differentiation, mitotic cycle, andoncogenic transformation. This PTP possesses an extracellularregion, a single transmembrane region, and a single intracellularcatalytic domain, and thus represents a receptor-type PTP. Thecatalytic domain of this PTP is most closely related toPTPRN/IA-2beta. This PTP and PTPRN are both found to be majorautoantigens associated with insulin-dependent diabetes mellitus.Three alternatively spliced transcript variants of this gene, whichencode distinct proteins, have been reported.
Protein Gi #
116242738
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Immunogen
This PTPRN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the N-terminal region of human PTPRN2.
Clonality
Polyclonal
NCBI Official Name
Receptor-type tyrosine-protein phosphatase N2
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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