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FBLN5 Antibody

ArtNr PRS-59-590-400ul
Hersteller ProSci
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Schneider, R., et al. J. Mol. Biol. 401(4):605-617(2010)
Zhou, S., et al. Biochem. Biophys. Res. Commun. 398(2):247-253(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
NCBI FBLN5
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Fibulin-5, FIBL-5, Developmental arteries and neural crest EGF-like protein, Dance, Urine p50 protein, UP50, FBLN5, DANCE
Lieferbar
Manufacturer - Applications
For WB starting dilution is: 1:1000
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
blue ice or room temperature
Storage Conditions
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
50 kDa
Manufacturer - Research Area
Signal Transduction
Background
The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motifand calcium-binding EGF-like domains. It promotes adhesion ofendothelial cells through interaction of integrins and the RGDmotif. It is prominently expressed in developing arteries but lessso in adult vessels. However, its expression is reinduced inballoon-injured vessels and atherosclerotic lesions, notably inintimal vascular smooth muscle cells and endothelial cells.Therefore, the protein encoded by this gene may play a role invascular development and remodeling. Defects in this gene are acause of autosomal dominant cutis laxa, autosomal recessive cutislaxa type I (CL type I), and age-related macular degeneration type3 (ARMD3).
Protein Gi #
12643876
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Immunogen
This FBLN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 393-421 amino acids from the C-terminal region of human FBLN5.
Clonality
Polyclonal
NCBI Official Name
Fibulin-5
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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