JAKMIP1 Antibody

Blue Ice

Predicted: 69 kDa

JAKMIP1 Antibody: JAKMIP1, also known as Marlin-1, is a highly-conserved vertebrate-specific microtubule-associated protein that plays a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. JAKMIP1 is expressed predominantly in neuronal and lymphoid cells and colocalizes with microtubules. Multiple isoforms of JAKMIP1 are known to exist: isoforms 1 and 5 are also expressed in liver, lung and skeletal muscle, while isoforms 2-4 are specifically expressed in brain and retina. JAKMIP1 participates in polarized secretion in lymphocytes and it has been suggested to be a novel effector memory gene restraining T cell-mediated cytotoxicity. Dysregulation of JAKMIP1 gene expression is associated with genetic conditions linked to autism in humans.

Trial Size

21389505

PRS-1463-0.1mg

JAKMIP1 Antibody is supplied in PBS containing 0.02% sodium azide.

Predicted species reactivity based on immunogen sequence: Bovine: (100%)

Rabbit polyclonal JAKMIP1 antibody was raised against a 16 amino acid peptide near the center of human JAKMIP1.

The immunogen is located within amino acids 260 - 310 of JAKMIP1.

janus kinase and microtubule interacting protein 1

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.