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JAKMIP1 Antibody

JAKMIP1 Antibody

Item no.	PRS-7165-0.02mg
Manufacturer	ProSci
Amount	0.02 mg
Quantity options	0.02 mg 0.1 mg
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Cell Biology Cell Status Western Blot ELISA Autophagy Primary Antibodies By Organ Lung Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	Costa V, Conte I, Ziviello C, et al. Identification and expression analysis of novel Jakmip1 transcripts. Gene 2007; 402:1-8. Vidal RL, Fuentes P, Valenzuela JI, et al. RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons. Mol. Cell Neurosci. 2012; epub. Libri V, Schulte D, Van Stijn A et al. Jakmip1 is expressed upon T cell differentiation and has an inhibitory function in cytotoxic T lymphocytes. J. Immunol. 2008; 181:5847-56 Bill BR, Geschwind DH. Genetic advances in autism: heterogeneity and convergence on shared pathways. Curr. Opin. Genet. Dev. 2009; 19:271-8.
NCBI	JAKMIP1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	JAKMIP1 Antibody: JAMIP1, MARLIN1, Gababrbp, GABABRBP, JAMIP1, Janus kinase and microtubule-interacting protein 1, GABA-B receptor-binding protein, Marlin-1
Available
Manufacturer - Applications	JAKMIP1 antibody can be used for detection of JAKMIP1 by Western blot at 1 - 2 μg/mL. Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.
Shipping Temperature	blue ice or room temperature
Storage Conditions	JAKMIP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Molecular Weight	Predicted: 69 kDa
Manufacturer - Research Area	Signal Transduction
Background	JAKMIP1 Antibody: JAKMIP1, also known as Marlin-1, is a highly-conserved vertebrate-specific microtubule-associated protein that plays a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. JAKMIP1 is expressed predominantly in neuronal and lymphoid cells and colocalizes with microtubules. Multiple isoforms of JAKMIP1 are known to exist: isoforms 1 and 5 are also expressed in liver, lung and skeletal muscle, while isoforms 2-4 are specifically expressed in brain and retina. JAKMIP1 participates in polarized secretion in lymphocytes and it has been suggested to be a novel effector memory gene restraining T cell-mediated cytotoxicity. Dysregulation of JAKMIP1 gene expression is associated with genetic conditions linked to autism in humans.
Protein Gi #	21389505
Purification	JAKMIP1 Antibody is affinity chromatography purified via peptide column.
Positive Control 1	PRS-1463-0.1mg
Concentration	1 mg/ml
Buffer	JAKMIP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Homology	Predicted species reactivity based on immunogen sequence: Bovine: (100%)
Immunogen	Rabbit polyclonal JAKMIP1 antibody was raised against a 16 amino acid peptide near the center of human JAKMIP1. The immunogen is located within amino acids 260 - 310 of JAKMIP1.
Clonality	Polyclonal
NCBI Official Name	janus kinase and microtubule interacting protein 1
NCBI Organism	homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.02 mg

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Delivery expected until 9/4/2025

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