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IL-15RA Antibody

ArtNr PRS-7233-0.1mg
Hersteller ProSci
Menge 0.1 mg
Quantity options 0.02 mg 0.1 mg
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
Citations Giri JG, Kumaki S, Ahdieh M, et al. Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor. EMBO J. 1995; 14:3654-63.
Bodnar A, Nizsaloczki E, Mocsar G, et al. A biophysical approach to IL-2 and IL-15 receptor function: localization, conformation and interactions. Immunol. Lett. 2008; 116:117-25.
Lorenz HM, Hieronymus T, Grunke M, et al. Differential role for IL-2 and IL-15 in the inhibition of apoptosis in short-term activated human lymphocytes. Scand. J. Immunol. 1997; 45:660-9.
NCBI IL15RA
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias IL-15RA Antibody: CD215,Interleukin-15 receptor subunit alpha,IL-15 receptor subunit alpha
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
IL-15RA antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Molecular Weight
Predicted: 26, 30, 38 kDa
Observed: 30 kDa
Manufacturer - Research Area
Immunology
Background
IL-15RA Antibody: Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity. IL-15 regulates T and natural killer cell activation and proliferation. The IL-15 and IL-2 receptors share two subunits, IL-2R beta and IL-2R gamma, and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high affinity IL-2 binding. Unlike IL-2RA, IL-15RA is capable of binding IL-15 with high affinity independent of the other subunits. IL-15RA is thought to enhance cell proliferation and expression of apoptosis inhibitor Bcl-xL and Bcl-2.
By Type
Immunology
Badges
Trial Size
Modifications
None
Protein Gi #
377520151
Purification
IL-15RA Antibody is affinity chromatography purified via peptide column.
Positive Control 1
Concentration
1 mg/mL
Buffer
IL-15RA Antibody is supplied in PBS containing 0.02% sodium azide.
Application Note
IL-15RA antibody can be used for detection of IL-15RA by Western blot at 1 - 2 μ g/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.
Manufacturer - Specificity
Multiple isoforms of IL-15RA are known to exist.
Immunogen
Rabbit polyclonal IL-15RA antibody was raised against a 16 amino acid peptide near the center of human IL-15RA.

The immunogen is located within amino acids 40 - 90 of IL-15RA.
Clonality
Polyclonal
NCBI Official Name
interleukin 15 receptor, alpha
NCBI Organism
homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
lieferbar

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