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IL-15RA Antibody

IL-15RA Antibody

Item no.	PRS-7233-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Quantity options	0.02 mg 0.1 mg
Category	Oncology Antibodies Cell Biology Cell Culture Cytokines Western Blot ELISA Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	Giri JG, Kumaki S, Ahdieh M, et al. Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor. EMBO J. 1995; 14:3654-63. Bodnar A, Nizsaloczki E, Mocsar G, et al. A biophysical approach to IL-2 and IL-15 receptor function: localization, conformation and interactions. Immunol. Lett. 2008; 116:117-25. Lorenz HM, Hieronymus T, Grunke M, et al. Differential role for IL-2 and IL-15 in the inhibition of apoptosis in short-term activated human lymphocytes. Scand. J. Immunol. 1997; 45:660-9.
NCBI	IL15RA
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	IL-15RA Antibody: CD215, Interleukin-15 receptor subunit alpha, IL-15 receptor subunit alpha
Available
Manufacturer - Applications	IL-15RA antibody can be used for detection of IL-15RA by Western blot at 1 - 2 μg/mL. Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.
Shipping Temperature	blue ice or room temperature
Storage Conditions	IL-15RA antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Molecular Weight	Predicted: 26, 30, 38 kDa Observed: 30 kDa
Manufacturer - Research Area	Immunology
Background	IL-15RA Antibody: Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity. IL-15 regulates T and natural killer cell activation and proliferation. The IL-15 and IL-2 receptors share two subunits, IL-2R beta and IL-2R gamma, and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high affinity IL-2 binding. Unlike IL-2RA, IL-15RA is capable of binding IL-15 with high affinity independent of the other subunits. IL-15RA is thought to enhance cell proliferation and expression of apoptosis inhibitor Bcl-xL and Bcl-2.
Protein Gi #	377520151
Purification	IL-15RA Antibody is affinity chromatography purified via peptide column.
Positive Control 1	PRS-1468-0.1mg
Concentration	1 mg/ml
Buffer	IL-15RA Antibody is supplied in PBS containing 0.02% sodium azide.
Immunogen	Rabbit polyclonal IL-15RA antibody was raised against a 16 amino acid peptide near the center of human IL-15RA. The immunogen is located within amino acids 40 - 90 of IL-15RA.
Clonality	Polyclonal
NCBI Official Name	interleukin 15 receptor, alpha
NCBI Organism	homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 9/4/2025

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