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F4/80 Antigen Antibody [BM8.1]

F4/80 Antigen Antibody [BM8.1]

ArtNr	PRS-76-052-0.1mg
Hersteller	ProSci
Menge	0.1 mg
Kategorie	Oncology Neuroscience Neuroinflammation Antibodies Flow Cytometry Immunohistochemistry Primary Antibodies By Organ Bone Cancer
Typ	Antibody Monoclonal
Format	liquid
Applikationen	FC, IHC
Clon	BM8.1
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a Kappa
Konjugat/Tag	Unconjugated
Citations	Zwadlo, G., Brcker, E. B., Von Bassewitz, D. B., Feige, U., Sorg, C. (1985). A monoclonal antibody to a differentiation antigen present on mature human macrophages and absent from monocytes.The Journal of Immunology,134(3), 1487-1492. Leenen, P. J., de Bruijn, M. F., Voerman, J. S., Campbell, P. A., van Ewijk, W. (1994). Markers of mouse macrophage development detected by monoclonal antibodies.Journal of immunological methods,174(1), 5-19. Schaller, E., Macfarlane, A. J., Rupec, R. A., Gordon, S., McKnight, A. J., Pfeffer, K. (2002). Inactivation of the F4/80 glycoprotein in the mouse germ line.Molecular and cellular biology,22(22), 8035-8043.
NCBI	Emr1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Ly71, F4/80, Gpf480, TM7LN3, DD7A5-7, EGF-TM7, Emr1
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Manufacturer - Isotype	Rat IgG2a, kappa
Shipping Temperature	blue ice or room temperature
Storage Conditions	The product should be stored undiluted at 4°C . Do not freeze.
Manufacturer - Research Area	Innate Immunity
Background	The BM8.1 monoclonal antibody specifically binds to the Mouse125 kDa F4/80 antigen, expressed by most mature macrophages. F4/80 is a transmembrane protein used as a marker of macrophages, although it is also expressed on Kupffer and Langerhans cells. The expression of F4/80 antigen is upregulated on bone marrow cells stimulated in vitro with the macrophage colony stimulating factor. The F4/80 antigen is a requirement for the induction of CD8 T cells-mediated peripheral tolerance.
Purification	The monoclonal antibody was purified utilizing affinity chromatography.
Concentration	Batch dependent
Buffer	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Clonality	Monoclonal
NCBI Official Name	EGF-like module containing, mucin-like, hormone receptor-like sequence 1
NCBI Organism	Mus musculus
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.1 mg

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