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CD3 Antibody [UCHT1] (APC-Cy7)

ArtNr PRS-76-300-25tests
Hersteller ProSci
Menge 25 tests
Kategorie
Typ Antibody Monoclonal
Format liquid
Applikationen FC
Clon UCHT1
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Konjugat/Tag Cy7, APC
Citations Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
McMichael, A. J. (1987). Leucocyte typing III.Oxford University Press, Oxford. Norton AJ, Isaacson PG (1985)
Beverley, P. C., Callard, R. E. (1981). Distinctive functional characteristics of human T lymphocytes defined by E rosetting or a monoclonal anti-T cell antibody.European journal of immunology,11(4), 329-334.
NCBI CD3E
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias T3E, TCRE, IMD18, CD3E
Lieferbar
Manufacturer - Isotype
Mouse IgG1, kappa
Shipping Temperature
blue ice or room temperature
Storage Conditions
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area
Immunology
Background
The UCHT1 monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains gamma, delta, and epsilon chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction. Unlike HIT3a, another specific antibody of CD3, the UCHT1 antibody can stain both the surface and intracellular CD3epsilon. The immobilized UCHT1 can cross-link with the TCR complex, enhancing cellular activation and proliferation.
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Clonality
Monoclonal
NCBI Official Name
CD3e molecule, epsilon (CD3-TCR complex)
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 25 tests
Lieferbar: In stock
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