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CD28 Antibody [CD28.2] (FITC)

CD28 Antibody [CD28.2] (FITC)

ArtNr	PRS-76-729-25tests
Hersteller	ProSci
Menge	25 tests
Kategorie	Neuroscience Neural Lineage Markers Aging & Neurological Disorders Antibodies Flow Cytometry Primary Antibodies
Typ	Antibody Monoclonal
Format	liquid
Applikationen	FC
Clon	CD28.2
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Konjugat/Tag	FITC
Citations	Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York Nuns, J., Klasen, S., Ragueneau, M., Pavon, C., Couez, D., Mawas, C., ... Olive, D. (1993). CD28 mAbs with distinct binding properties differ in their ability to induce T cell activation: analysis of early and late activation events.International immunology,5(3), 311-315. Karlsson, I., Malleret, B., Brochard, P., Delache, B., Calvo, J., Le Grand, R., Vaslin, B. (2007). FoxP3+ CD25+ CD8+ T-cell induction during primary simian immunodeficiency virus infection in cynomolgus macaques correlates with low CD4+ T-cell activation and high viral load.Journal of virology,81(24), 13444-13455.
NCBI	CD28
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Tp44, CD28
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Manufacturer - Isotype	Mouse IgG1, kappa
Shipping Temperature	blue ice or room temperature
Storage Conditions	The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area	Immunology
Background	The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes. CD28 is a ligand for B7-1 (CD80) and B7-2 (CD86), a co-stimulator of T lymphocytes, and enhances the interaction between T and B lymphocytes. It has been reported that the T lymphocytes stimulation to produce IL-2 depends on the monoclonal antibody involved, which suggests that the CD28 molecule presents some subregions with distinct functions. The CD28.2 antibody induces Ca2+ influx in Jurkat T lymphocytes. Other studies have shown that CD28 is involved in the signal transduction.
Purification	The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration	Batch dependent
Buffer	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Clonality	Monoclonal
NCBI Official Name	CD28 molecule
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 25 tests

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Lieferung vsl. bis 04.09.2025

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