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PIK3C3 Antibody

ArtNr PRS-7891-0.02mg
Hersteller ProSci
Menge 0.02 mg
Quantity options 0.02 mg 0.1 mg
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
Citations Stopkova P, Saito T, Papolos DF, et al. Identification of PIK3C3 promoter variant associated with bipolar disorder and schizophrenia. Biol. Psychiatry 2004; 55:981-8.
Hal BS, Gabernet-Castello C, Voak A, et al. TbVps34, the trypanosome orthologue of Vps34, is required for Golgi complex segregation. J. Biol. Chem. 2006; 281:27600-12.
Backer JM. The regulation and function of class III PI3Ks: novel roles for Vps34. Biochem. J. 2008; 410:1-17.
Jaber N, Dou Z, Lin RZ, et al. Mammalian PIK3C3/VPS34: the key to autophagic processing in liver and heart. Autophagy 2012; 8:707-8.
NCBI PIK3C3
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias PIK3C3 Antibody: VPS34,hVps34,VPS34,Phosphatidylinositol 3-kinase catalytic subunit type 3,Phosphatidylinositol 3-kinase p100 subunit,PI3-kinase type 3
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
PIK3C3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Molecular Weight
Predicted: 91, 98 kDa
Observed: 98 kDa
Manufacturer - Research Area
Autophagy
Background
PI 3-kinase p100 (phosphoinositide-3-kinase p100 subunit), also known as hVps34 or PIK3C3 (phosphoinositide-3-kinase class III), is a member of the PI3/PI4-kinase family (1). It is a catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate and ubiquitously expressed with a highest expression in skeletal muscle (1, 2). PIK3C3 is involved in the endosome to lysosome transport and plays important roles in intracellular membrane trafficking and autophagy (3-5).
By Type
Autophagy
Badges
Trial Size
Modifications
None
Protein Gi #
34761064
Purification
PIK3C3 antibody is affinity chromatography purified via peptide column.
Positive Control 1
Concentration
1 mg/mL
Buffer
PIK3C3 antibody is supplied in PBS containing 0.02% sodium azide.
Application Note
PIK3C3 antibody can be used for detection of PIK3C3 by Western blot at 1 - 2 μ g/ml.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
Homology
Predicted species reactivity based on immunogen sequence: Pig: (100%)
Manufacturer - Specificity
PIK3C3 antibody is human, mouse and rat reactive.
Immunogen
PIK3C3 antibody was raised against an 18 amino acid peptide near the amino terminus of human PIK3C3.

The immunogen is located within amino acids 130 - 180 of PIK3C3.
Clonality
Polyclonal
NCBI Official Name
phosphatidylinositol 3-kinase, catalytic subunit type 3
NCBI Organism
homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.02 mg
Lieferbar: In stock
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