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PIK3C3 Antibody

PIK3C3 Antibody

Item no.	PRS-7891-0.02mg
Manufacturer	ProSci
Amount	0.02 mg
Quantity options	0.02 mg 0.1 mg
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Adenocarcinoma Mesothelioma Western Blot ELISA Autophagy Cardiovascular Research Proliferation Myocardial Infarction Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	Stopkova P, Saito T, Papolos DF, et al. Identification of PIK3C3 promoter variant associated with bipolar disorder and schizophrenia. Biol. Psychiatry 2004; 55:981-8. Hal BS, Gabernet-Castello C, Voak A, et al. TbVps34, the trypanosome orthologue of Vps34, is required for Golgi complex segregation. J. Biol. Chem. 2006; 281:27600-12. Backer JM. The regulation and function of class III PI3Ks: novel roles for Vps34. Biochem. J. 2008; 410:1-17. Jaber N, Dou Z, Lin RZ, et al. Mammalian PIK3C3/VPS34: the key to autophagic processing in liver and heart. Autophagy 2012; 8:707-8.
NCBI	PIK3C3
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PIK3C3 Antibody: VPS34, hVps34, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, PI3-kinase type 3
Available
Manufacturer - Applications	PIK3C3 antibody can be used for detection of PIK3C3 by Western blot at 1 - 2 μg/ml. Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
Shipping Temperature	blue ice or room temperature
Storage Conditions	PIK3C3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Molecular Weight	Predicted: 91, 98 kDa Observed: 98 kDa
Manufacturer - Research Area	Autophagy
Background	PI 3-kinase p100 (phosphoinositide-3-kinase p100 subunit), also known as hVps34 or PIK3C3 (phosphoinositide-3-kinase class III), is a member of the PI3/PI4-kinase family (1). It is a catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate and ubiquitously expressed with a highest expression in skeletal muscle (1, 2). PIK3C3 is involved in the endosome to lysosome transport and plays important roles in intracellular membrane trafficking and autophagy (3-5).
Protein Gi #	34761064
Purification	PIK3C3 antibody is affinity chromatography purified via peptide column.
Positive Control 1	PRS-1408-0.1mg
Concentration	1 mg/ml
Buffer	PIK3C3 antibody is supplied in PBS containing 0.02% sodium azide.
Homology	Predicted species reactivity based on immunogen sequence: Pig: (100%)
Immunogen	PIK3C3 antibody was raised against an 18 amino acid peptide near the amino terminus of human PIK3C3. The immunogen is located within amino acids 130 - 180 of PIK3C3.
Clonality	Polyclonal
NCBI Official Name	phosphatidylinositol 3-kinase, catalytic subunit type 3
NCBI Organism	homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.02 mg

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Delivery expected until 9/4/2025

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