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Tyrosine Hydroxylase (phospho Ser40) Antibody

Tyrosine Hydroxylase (phospho Ser40) Antibody

ArtNr	PRS-XPS-1033-0.1mL
Hersteller	ProSci
Menge	0.1 mL
Kategorie	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Signaling Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies Neuronal Cell Markers
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Monkey (Cynomolgus, Simian), Pig (Porcine, Sus scrofa domesticus)
Host	Rabbit
Konjugat/Tag	Unconjugated
Citations	Witkovsky, P., Gabriel, R., Haycock, J. W., and Meller, E., "Influence of light and neural circuitry on tyrosine hydroxylase phosphorylation in the rat retina," J. Chem. Neuroanat., 19 (2000) 105 - 116. Haycock, J. W., Lew, J. Y., Garcia-Espana, A., Lee, K. Y., Harada, K., Meller, E., and Goldstein, M., "Role of serine-19 phosphorylation in regulating tyrosine hydroxylase studied with site- and phosphospecific antibodies and site-directed mutagenesis," J. Neurochem., 71 (1998) 1670-1675. Xu, Z.-Q., Lew, J. Y., Harada, K., Aman, K., Goldstein, M., Deutch, A., Haycock, J. W., and Hokfelt, T., "Immunohistochemical studies on phosphorylation of tyrosine hydroxylase in central catecholamine neurons using site- and phosphorylation state-specific antibodies," Neuroscience, 82 (1998) 727-738.
NCBI	Th
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
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Manufacturer - Applications	Applications include Immunofluorescence (IF), Immunohistochemistry (IHC) and Western Blots (WB). Human, porcine, quail, mouse, and non-human primate have 100% amino acid sequence identity with the antigen used to raise the antibody. When internally tested under ideal conditions the working dilutions were 1:1000 for IF, IHC and WB.
Shipping Temperature	blue ice or room temperature
Storage Conditions	For long term storage –80°C is recommended, but shorter term storage at –20°C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol. Stable for one year.
Molecular Weight	60
Manufacturer - Research Area	Neuroscience , Signal Transduction , Phospho-Specific
Background	Tyrosine Hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines Dopamine and Norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons. We raised this polyclonal antibody against a peptide representing the sequence around Ser40 in rat TH. This antibody is suitable for most immunochemical applications in a variety of mammalian and some non-mammalian species.
Modifications	Phospho-Specific
Protein Gi #	136577
Purification	Affinity Purified
Immunogen	TH (Ser40) polyclonal antibody was raised against a synthetic phosphopeptide corresponding to amino acids residues surrounding the phospho-Ser40 of rat tyrosine hydroxylase (TH).
Clonality	Polyclonal
NCBI Official Name	tyrosine hydroxylase
NCBI Organism	Rattus norvegicus
Disclaimer	This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.1 mL

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