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Mouse Activin RIIA/ACVR2A Protein (ARA-MM12A)

ArtNr ARA-MM12A-500UG
Hersteller KactusBio
Menge 500 ug
Quantity options 100 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against Mouse (Murine, Mus musculus)
Host HEK293
Konjugat/Tag HIS
Purity > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Sequence Ala20-Pro135
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Lieferbar
Manufacturer - Product Type
Recombinant Protein
Description
Recombinant Mouse Activin RIIA/ACVR2A Protein is expressed from HEK293 with His tag at the C-terminus; It contains Ala20-Pro135.
Background
Activin A receptor type 2A (ACVR2A) is a membrane receptor in the transforming growth factor- beta (TGF-β signaling pathway, which is involved in the regulation of cell proliferation, migration, and apoptosis. Loss of ACVR2A has an important role in cancer progression and distant metastasis and may serve as a prognostic marker in patients with colon cancer.
Endotoxin
Less than 1 EU per μg by the LAL method.
Molecular Weight
The protein has a predicted MW of 15.06 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.
Target
Activin RIIA/ACVR2A
Manufacturer - Tag
C-His
Stability and Storage
-20 to -80°C for 12 months as supplied from date of receipt; -80°C for 3-6 months after reconstitution; 2-8°C for 2-7 days after reconstitution; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Biotinylated
no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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