Anti-Cyclin G1 Polyclonal Antibody (OAAI00026)

CCNG1

900

The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The Cyclin G contains a typical N terminal cyclin box and a carboxy terminal domain sequence homologous to the tyrosine phosphorylation site of the epidermal growth factor receptor. Cyclin G2 shares 53% amino acid sequence identity with cyclin G1. Peak expression of cyclin G2 is seen in late S phase, as opposed to cyclin G1 expression. It is p53-responsive gene that the transcriptional activation of Cyclin G1 can be induced by tumor protein p53.

Polyclonal

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