LTBR Antibody (OAED00352)

LTBR

4055

The LTbetaR activates two different NF-κ B pathways that lead to distinct patterns of gene induction, including selected chemokines, and the cytokine BAFF, which is essential for the survival of mature B lymphocytes.A LTbetaR activates the classical NF-κ B (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta.A However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.

Liquid. In PBS containing 0.02% sodium azide.

a‰¥95% (SDS-PAGE)