CHD3 Antibody - N-terminal region (OAAB21037)

227 kDa

1107

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Protein A column purification, followed by peptide affinity purification

Purified polyclonal antibody, supplied in PBS with 0.09% sodium azide.

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