NR1H2 Antibody

ArtNr	OACA09439
Hersteller	AVIVA Systems Biology
Menge	50 ug
Kategorie	Neuroscience Metabolism Cholesterol & Lipid Metabolism Targets for Rodent Neurosciences Antibodies Obesity Immunohistochemistry Western Blot ELISA Immunofluorescence Lipoprotein Receptors & Associated Proteins Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	liver X nuclear receptor beta;Liver X receptor beta;LX receptor beta;LXR-b;LXRB;NER;NER-I;nuclear orphan receptor LXR-beta;nuclear receptor NER;Nuclear receptor subfamily 1 group H member 2;oxysterols receptor LXR-beta;RIP15;steroid hormone-nuclear receptor NER;ubiquitously-expressed nuclear receptor;UNR.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	NR1H2
Gene Fullname	nuclear receptor subfamily 1 group H member 2
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity (PubMed:25661920). Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8; DLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex (PubMed:20159957).
Nucleotide accession_num	NM_001256647
Protein accession_num	NP_001243576
Protein name	Oxysterols receptor LXR-beta
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Oxysterols receptor LXR-beta protein (1-461AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

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OACA09439-datasheet.pdf

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Menge: 50 ug

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Lieferung vsl. bis 25.12.2025

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