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NR1H2 Antibody

NR1H2 Antibody

Item no.	OACA09439
Manufacturer	AVIVA Systems Biology
Amount	50 ug
Category	Neuroscience Metabolism Cholesterol & Lipid Metabolism Targets for Rodent Neurosciences Antibodies Obesity Immunohistochemistry Western Blot ELISA Immunofluorescence Lipoprotein Receptors & Associated Proteins Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	liver X nuclear receptor beta;Liver X receptor beta;LX receptor beta;LXR-b;LXRB;NER;NER-I;nuclear orphan receptor LXR-beta;nuclear receptor NER;Nuclear receptor subfamily 1 group H member 2;oxysterols receptor LXR-beta;RIP15;steroid hormone-nuclear receptor NER;ubiquitously-expressed nuclear receptor;UNR.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	NR1H2
Gene Fullname	nuclear receptor subfamily 1 group H member 2
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity (PubMed:25661920). Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8; DLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex (PubMed:20159957).
Nucleotide accession_num	NM_001256647
Protein accession_num	NP_001243576
Protein name	Oxysterols receptor LXR-beta
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Oxysterols receptor LXR-beta protein (1-461AA)
Formulation	50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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