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GRPR Peptide - N-terminal region (AAP76236)

GRPR Peptide - N-terminal region (AAP76236)

ArtNr	AAP76236
Hersteller	AVIVA Systems Biology
Menge	100ug
Kategorie	Oncology Peptides & Proteins Peptides By Organ Lung Cancer
Typ	Peptides
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
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Description	This is a synthetic peptide designed for use in combination with anti-GRPR Antibody (ARP76236_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol	GRPR
Protein size	384
Molecular weight	43kDa
Product format	Lyophilized powder
Gene id	2925
Reconstitution and storage	Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Description of target	Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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AAP76236-datasheet.pdf

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Menge: 100ug

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Lieferung vsl. bis 11.09.2025

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