ZFPM1 Antibody

Ice packs

For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

The antiserum was purified by peptide affinity chromatography.

Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2 (By similarity).

WB 1:500-1:2000

ZFPM1 antibody detects endogenous levels of total ZFPM1