HP Antibody

Ice packs

For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

The antiserum was purified by peptide affinity chromatography.

As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC: 1:100-1:500

HP Antibody detects endogenous levels of total HP