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Recombinant Human Fibroblast growth factor 2 protein (FGF2) (Active)

Recombinant Human Fibroblast growth factor 2 protein (FGF2) (Active)

ArtNr	BM-RPC26668-50ug
Hersteller	Biomatik
Menge	50ug
Kategorie	Oncology Neuroscience Neural Adhesion Molecules By Cell Type Carcinoma Hematology Leukemia Myeloma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines By Organ Bladder Cancer
Typ	Proteins Recombinant
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	FGF-2, bFGF, Heparin-binding growth factor 2, HBGF-2,
Similar products	bFGF, Heparin-binding growth factor 2, HBGF-2, FGF-2
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Gene Name	FGF2, FGFB
Alternative Names	FGF-2, bFGF, Heparin-binding growth factor 2, HBGF-2,
Uniprot	P09038
Source	E.coli
Expression Region	143-288aa
AA Sequence	M+PALPEDGGS GAFPPGHFKD PKRLYCKNGG F FLRIHPDGR VDGVREKSDP HIKLQLQAEE RGV VSIKGVC ANRYLAMKED GRLLASKCVT DECFF FERLE SNNYNTYRSR KYTSWYVALK RTGQYKL GSK TGPGQKAILF LPMSAKS
Sequence Info	Full Length of Mature Protein
Tag Info	Tag-Free
Theoretical MW	16.5 kDa
Purity	>96% as determined by SDS-PAGE and HPLC.
Storage Buffer	Lyophilized from a 0.2 um filtered 20 mM Tris-HCl, pH 7.6, with 150mM NaCl
Endotoxin Level	Less than 1.0 EU/ug as determined by LAL method.
Biological Activity	The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 0.05 ng/ml, corresponding to a specific activity of ? 2.0 x 107 IU/mg.
Shipping Condition	Ice packs
Storage	Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles.
Expiry Date	1 year
Restriction	For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance	Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. {ECO:0000269\|PubMed:1721615, ECO:0000269\|PubMed:8663044}.
Function	Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Can induce angiogenesis
Subcellular location	Secreted, Nucleus
Protein Families	Heparin-binding growth factors family
Tissue Specificity	Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non-cancerous liver tissue.
Paythway	MAPKsignalingpathway

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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