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Recombinant Neosartorya fumigata Alkaline protease 1 (alp1)

ArtNr BM-RPC26092-1mg
Hersteller Biomatik
Menge 1mg
Kategorie
Typ Proteins Recombinant
Specific against other
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Aspergillopeptidase B (Aspergillus proteinase B) (Elastase) (Elastinolytic serine proteinase) (Oryzin) (Allergen: Asp f 13) (ALP) (alk1) (alp)
Similar products Aspergillopeptidase B (Aspergillus proteinase B) (Elastase) (Elastinolytic serine proteinase) (Oryzin) (Allergen: Asp f 13) (ALP) (alk1) (alp)
Lieferbar
Gene Name
alp1
Alternative Names
Aspergillopeptidase B (Aspergillus proteinase B) (Elastase) (Elastinolytic serine proteinase) (Oryzin) (Allergen: Asp f 13) (ALP) (alk1) (alp)
Uniprot
P28296
Source
E.coli
Expression Region
102-403aa
AA Sequence
EIRKSADVAHVEEDQIWYLDALTTQKGAPWGLGSI SHKGQASTDYIYDTSAGAGTYAYVVDSGINVNHVE FESRASLAYNAAGGSHVDSIGHGTHVAGTIGGKTY GVAKKTNLLSVKVFQGESSSTSIILDGFNWAVNDI VSKGRTKKAAINMSLGGGYSYAFNNAVENAFDEGV LSVVAAGNENSDASNTSPASAPNALTVAAINKSNA RASFSNYGSVVDIFAPGQDILSAWIGSTTATNTIS GTSMATPHIVGLSVYLMGLENLSGPAAVTARIKEL ATNGVVTNVKGSPNKLAYNGNA
Sequence Info
Full Length of Mature Protein
Tag Info
N-terminal 10xHis-tagged and C-terminal Myc-tagged
Theoretical MW
38.5 kDa
Purity
>85% as determined by SDS-PAGE.
Storage Buffer
Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Endotoxin Level
Not tested
Biological Activity
Not tested
Shipping Condition
Ice packs
Storage
Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles.
Expiry Date
1 year
Restriction
For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance
Secreted alkaline protease that allows assimilation of proteinaceous substrates. Acts as a significant virulence factor in invasive aspergillosis. Involved in immune evasion from the human and mice complement systems during infection. Efficiently cleaves important components of the complement cascade such as such as C3, C4, C5, and C1q, as well as IgG, which leads to down-regulation of complement activation at the hyphal surface.
Function
Secreted alkaline protease that allows assimilation of proteinaceous substrates. Acts as a significant virulence factor in invasive aspergillosis. Involved in immune evasion from the human and mice complement systems during infection. Efficiently cleaves important components of the complement cascade such as such as C3, C4, C5, and C1q, as well as IgG, which leads to down-regulation of complement activation at the hyphal surface.
Subcellular location
Secreted
Protein Families
Peptidase S8 family

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1mg
Lieferbar: In stock
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