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Anti-Calbindin/CALB1 Antibody Picoband®

Anti-Calbindin/CALB1 Antibody Picoband®

ArtNr	BOS-A03047-Fluoro550
Hersteller	Boster
Menge	100 ug/vial
Quantity options	100 ug/vial 10 ug 100 ug/vial 100 ug/vial 100 ug/vial 100 ug 100 ug 100 ug 100 ug/vial 100 ug/vial 100 ug/vial 100 ug/vial 100 ug/vial
Typ	Antibody Polyclonal
Format	Lyophilized
Applikationen	FC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	1. Parmentier M.; The human calbindins: cDNA and gene cloning.;Adv. Exp. Med. Biol. 255:233-240(1989). 2. Strauss K.I., Kuznicki J., Winsky L., Kawagoe J.I., Hammer M., Jacobowitz D.M.;The mouse calretinin gene promoter region: structural and functional components.;Brain Res. Mol. Brain Res. 49:175-187(1997). 3. Gabrielides C., McCormack A.L., Hunt D.F., Christakos S.;Brain calbindin-D28k and an Mr 29,000 calcium binding protein in cerebellum are different but related proteins: evidence obtained from sequence analysis by tandem mass spectrometry.;Biochemistry 30:656-662(1991).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Calbindin,Calbindin D28,D-28K,Vitamin D-dependent calcium-binding protein,avian-type,CALB1,CAB27
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Calculated Molecular weight	30, 025 MW
Clonality	Polyclonal
Gene Name	CALB1
Gene Full Name	calbindin 1, 28kDa
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Calbindin is a calcium-binding protein belonging to the troponin C superfamily. And it mapped to 8q21.3. Calretinin is expressed in central and peripheral nervous system and in many normal and pathological tissues. The rat and human calretinin exhibit 98% sequence homology and 91% homology to many other species. Two calcium binding proteins, calbindin and calretinin, have been reported to be expressed in abundance in Purkinje cells and other cell types in the cerebellum.
Immunogen	E. coli-derived human Calbindin recombinant protein (Position: A2-N261).
Contents	Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Purification	Immunogen affinity purified.
Manufacturer - Research Category	Calcium Binding Proteins, Calcium Signaling, Cell Type Marker, Neuron Marker, Neuroscience, Neurotransmission
Protein Function	Buffers cytosolic calcium. May stimulate a membrane Ca (2+)-ATPase and a 3', 5'-cyclic nucleotide phosphodiesterase.
Subcellular Localization	Hemidesmosome, Membrane, Single-pass type II membrane protein, Basement membrane.
Tissue Specificity	Detected in skin. In the cornea, it is detected in the epithelial basement membrane, the epithelial cells, and at a lower level in stromal cells. Stratified squamous epithelia. Found in hemidesmosomes. Expressed in cornea, oral mucosa, esophagus, intestine, kidney collecting ducts, ureter, bladder, urethra and thymus but is absent in lung, blood vessels, skeletal muscle and nerves.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-A03047-Fluoro550-datasheet.pdf

BOS-A03047-Fluoro550-safety-datasheet.pdf