Anti-USP19 Antibody

ArtNr	BOS-A05870-1
Hersteller	Boster
Menge	100 ul
Quantity options	100 ul 100 ul 100 ul
Kategorie	Food Safety Hormones Neuroscience Targets for Rodent Neurosciences Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Typ	Antibody
Format	Liquid
Applikationen	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Ubiquitin carboxyl-terminal hydrolase 19,3.4.19.12,Deubiquitinating enzyme 19,Ubiquitin thioesterase 19,Ubiquitin-specific-processing protease 19,Zinc finger MYND domain-containing protein 9,USP19,KIAA0891,ZMYND9
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	145651 MW
Application Details	WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:20000 IF 1:50-200
Gene Name	USP19
Gene Full Name	Ubiquitin carboxyl-terminal hydrolase 19
Immunogen	The antiserum was produced against synthesized peptide derived from human USP19. AA range:391-440
Contents	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	Immunogen affinity purified
Concentration	1 mg/ml
Protein Function	Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin- dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic- reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non- catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains.
Subcellular Localization	Endoplasmic reticulum membrane ; Single-pass membrane protein.
Description	Boster Bio Anti-USP19 Antibody catalog # A05870-1. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Short Description	Boster Bio Anti-USP19 Antibody catalog # A05870-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

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BOS-A05870-1-datasheet.pdf

BOS-A05870-1-safety-datasheet.pdf