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Anti-CXCR2 Antibody Picoband® Europäischer Partner

ArtNr BOS-PA1029-PE
Hersteller Boster
Menge 100 ug
Quantity options 100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB
Specific against Human (Homo sapiens), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag PE
Sensitivity <10 pg/ml
Sequence Belongs to the G-protein coupled receptor 1 family.
Citations 1. Murphy P.M., Tiffany H.L.;Cloning of complementary DNA encoding a functional human interleukin-8 receptor.; Science 253:1280-1283(1991).
2. Cerretti D.P., Kozlosky C.J., Vanden Bos T., Nelson N., Gearing D.P., Beckmann M.P.;
Molecular characterization of receptors for human interleukin-8, GRO/melanoma growth-stimulatory activity and neutrophil activating peptide-2.; Mol. Immunol. 30:359-367(1993).
3. Sprenger H., Lloyd A.R., Lautens L.L., Bonner T.I., Kelvin D.J.;Structure, genomic organization, and expression of the human interleukin-8 receptor B gene.;J. Biol. Chem. 269:11065-11072(1994).
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias C-X-C chemokine receptor type 2,CXC-R2,CXCR-2,CDw128b,GRO/MGSA receptor,High affinity interleukin-8 receptor B,IL-8R B,IL-8 receptor type 2,CD182,CXCR2,IL8RB
Lieferbar
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
45 kDa
Calculated Molecular weight
40759 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5μg/ml, Human, Rat
Gene Name
CXCR2
Gene Full Name
C-X-C chemokine receptor type 2
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family (subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human CXCR2, different from the related mouse sequence by six amino acids.
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
Cell Biology, Cell Cycle, Cell Division, G Protein Signaling, Signal Transduction, Signaling Pathway
Protein Name
C-X-C chemokine receptor type 2(CXC-R2/CXCR-2)
Protein Function
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Subcellular Localization
Cell membrane; Multi-pass membrane protein.
Description
Boster Bio Anti-CXCR2 Antibody catalog # PA1029. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Found in plasma.
Sequence Similarities
Belongs to the G-protein coupled receptor 1 family.
Manufacturer - Cross Reactivity
No cross-reactivity with other proteins

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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