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Anti-CXCR2 Antibody Picoband® Europäischer Partner

ArtNr BOS-PA1029
Hersteller Boster
Menge 100 ug/vial
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB
Specific against Human (Homo sapiens), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity <10pg/ml
Citations 1. Murphy P.M., Tiffany H.L.;"Cloning of complementary DNA encoding a functional human interleukin-8 receptor."; Science 253:1280-1283(1991).
2. Cerretti D.P., Kozlosky C.J., Vanden Bos T., Nelson N., Gearing D.P., Beckmann M.P.;
"Molecular characterization of receptors for human interleukin-8, GRO/melanoma growth-stimulatory activity and neutrophil activating peptide-2."; Mol. Immunol. 30:359-367(1993).
3. Sprenger H., Lloyd A.R., Lautens L.L., Bonner T.I., Kelvin D.J.;"Structure, genomic organization, and expression of the human interleukin-8 receptor B gene.";J. Biol. Chem. 269:11065-11072(1994).
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias C-X-C chemokine receptor type 2;CXC-R2;CXCR-2;CDw128b;GRO/MGSA receptor;High affinity interleukin-8 receptor B;IL-8R B;IL-8 receptor type 2;CD182;CXCR2;IL8RB;
Similar products C-X-C chemokine receptor type 2 antibody, CD 182 antibody, CD182 antibody, CD182 antigen antibody, CDw128b antibody, Chemokine(CXC) receptor 2 antibody, CMKAR2 antibody, CXC-R2 antibody, CXCR 2 antibody, CXCR-2 antibody, CXCR2 antibody, CXCR2_HUMAN antibody, GRO/MGSA receptor antibody, High affinity interleukin-8 receptor B antibody, IL 8 receptor type 2 antibody, IL 8R B antibody, IL-8 receptor type 2 antibody, IL-8R B antibody, IL8 RB antibody, IL8 receptor type 2 antibody, IL8R B antibody, IL8R2 antibody, IL8RA antibody, Interleukin 8 Receptor B antibody
Lieferbar
Specificity No cross reactivity with other proteins.
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
45 kDa
Calculated Molecular weight
40759 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5?g/ml, Human, Rat
Manufacturer - Gene Name
CXCR2
Gene Full Name
C-X-C chemokine receptor type 2
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family (subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human CXCR2, different from the related mouse sequence by six amino acids.
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Cell Biology, Cell Cycle, Cell Division, G Protein Signaling, Signal Transduction, Signaling Pathway
Protein Name
C-X-C chemokine receptor type 2(CXC-R2/CXCR-2)
Protein Function
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Subcellular Localization
Cell membrane; Multi-pass membrane protein.
Description
Boster Bio Anti-CXCR2 Antibody catalog # PA1029. Tested in WB applications. This antibody reacts with Human, Rat.
Tissue Specificity
Found in plasma.
Sequence Similarities
Belongs to the G-protein coupled receptor 1 family.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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