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Anti-BAFF Receptor/TNFRSF13C Antibody Picoband® Europäischer Partner

ArtNr BOS-PA1391-10ug
Hersteller Boster
Menge 10 ug
Quantity options 100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Sensitivity <10 pg/ml
Citations 1. Thompson JS, Bixler SA, Qian F, Vora K, Scott ML, Cachero TG, Hession C, Schneider P, Sizing ID, Mullen C, Strauch K, Zafari M, Benjamin CD, Tschopp J, Browning JL, Ambrose C (Sep 2001). "BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF". Science 293 (5537): 2108–11. doi:10.1126/science.1061965. PMID 11509692.
2. Entrez Gene: TNFRSF13C tumor necrosis factor receptor superfamily, member 13C".
3. Schiemann, B., Gommerman, J. L., Vora, K., Cachero, T. G., Shulga-Morskaya, S., Dobles, M., Frew, E., Scott, M. L.An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway.Science293: 2111-2114, 2001.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Tumor necrosis factor receptor superfamily member 13C,B-cell-activating factor receptor,BAFF receptor,BAFF-R,BLyS receptor 3,CD268,TNFRSF13C,BAFFR,BR3
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Molecular Weight
40 kDa
Calculated Molecular weight
18864 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5μg/ml, Human
Gene Name
TNFRSF13C
Gene Full Name
Tumor necrosis factor receptor superfamily member 13C
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), also known as BAFFR, is a protein in humans is encoded by the TNFRSF13C gene. The BAFFR gene is mapped to chromosome 22q13.1-q13.31. It has got 184 amino acid transmembrane protein which is 56% identical to the mouse protein. B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. BAFF plays a crucial role in B cell development and can function through receptors other than BCMA.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human BAFF Receptor.
Contents
Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category
Growth Factors/Hormones, Signal Transduction
Protein Name
Tumor necrosis factor receptor superfamily member 13C
Protein Function
B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.
Subcellular Localization
Membrane ; Single-pass type III membrane protein.
Description
Boster Bio Anti-BAFF Receptor/TNFRSF13C Antibody catalog # PA1391. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Highly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes.
Sequence Similarities
Belongs to the short-chain dehydrogenases/reductases (SDR) family.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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