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Anti-BAFF Receptor/TNFRSF13C Antibody Picoband®

Anti-BAFF Receptor/TNFRSF13C Antibody Picoband®

ArtNr	BOS-PA1391
Hersteller	Boster
Menge	100 ug/vial
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Aging & Neurological Disorders Antibodies By Cell Type Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Format	Lyophilized
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Sensitivity	<10pg/ml
Citations	1. Thompson JS, Bixler SA, Qian F, Vora K, Scott ML, Cachero TG, Hession C, Schneider P, Sizing ID, Mullen C, Strauch K, Zafari M, Benjamin CD, Tschopp J, Browning JL, Ambrose C (Sep 2001). "BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF". Science 293 (5537): 2108–11. doi:10.1126/science.1061965. PMID 11509692. 2. Entrez Gene: TNFRSF13C tumor necrosis factor receptor superfamily, member 13C". 3. Schiemann, B., Gommerman, J. L., Vora, K., Cachero, T. G., Shulga-Morskaya, S., Dobles, M., Frew, E., Scott, M. L.An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway.Science293: 2111-2114, 2001.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Tumor necrosis factor receptor superfamily member 13C;B-cell-activating factor receptor;BAFF receptor;BAFF-R;BLyS receptor 3;CD268;TNFRSF13C;BAFFR, BR3;
Similar products	B Cell Activating Factor Receptor antibody, B-cell-activating factor receptor antibody, BAFF R antibody, BAFF receptor antibody, BAFF-R antibody, BAFFR antibody, BLyS receptor 3 antibody, BlySR3 antibody, BR 3 antibody, BR3 antibody, BROMIX antibody, CD 268 antibody, CD268 antibody, CD268 antigen antibody, CVID4 antibody, MGC138235 antibody, OTTHUMP00000028746 antibody, Prolixin antibody, TNFRSF 13C antibody, TNFRSF13C antibody, TR13C_HUMAN antibody, Tumor Necrosis Factor Receptor Subunit Member 13C antibody, Tumor necrosis factor receptor superfamily member 13C antibody
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	40 kDa
Calculated Molecular weight	18864 MW
Clonality	Polyclonal
Application Details	Western blot, 0.1-0.5?g/ml, Human
Manufacturer - Gene Name	TNFRSF13C
Gene Full Name	Tumor necrosis factor receptor superfamily member 13C
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), also known as BAFFR, is a protein in humans is encoded by the TNFRSF13C gene. The BAFFR gene is mapped to chromosome 22q13.1-q13.31. It has got 184 amino acid transmembrane protein which is 56% identical to the mouse protein. B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. BAFF plays a crucial role in B cell development and can function through receptors other than BCMA.
Immunogen	A synthetic peptide corresponding to a sequence at the N-terminus of human BAFF Receptor.
Contents	Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category	Growth Factors/Hormones, Signal Transduction
Protein Name	Tumor necrosis factor receptor superfamily member 13C
Protein Function	B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.
Subcellular Localization	Membrane; Single-pass type III membrane protein.
Description	Boster Bio Anti-BAFF Receptor/TNFRSF13C Antibody catalog # PA1391. Tested in WB applications. This antibody reacts with Human.
Tissue Specificity	Highly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes.
Sequence Similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family.

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