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Anti-Calbindin/CALB1 Antibody Picoband®

Anti-Calbindin/CALB1 Antibody Picoband®

ArtNr	BOS-PB9045-iFluor647
Hersteller	Boster
Menge	100 ug
Quantity options	100 ug/vial 10 ug 100 ug/vial 100 ug/vial 100 ug/vial 100 ug 100 ug 100 ug 100 ug/vial 100 ug/vial 100 ug/vial 100 ug/vial 100 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunofluorescence Primary Antibodies By Organ Brain Cancer Immunostaining Calcium Binding Protein Markers Neurodegeneration Markers Microglia Markers
Typ	Antibody Polyclonal
Format	Lyophilized
Applikationen	WB, IP, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	>5000 cells
Sequence	Belongs to the calbindin family.
Citations	1. Parmentier M.; The human calbindins: cDNA and gene cloning.;Adv. Exp. Med. Biol. 255:233-240(1989). 2. Strauss K.I., Kuznicki J., Winsky L., Kawagoe J.I., Hammer M., Jacobowitz D.M.;The mouse calretinin gene promoter region: structural and functional components.;Brain Res. Mol. Brain Res. 49:175-187(1997). 3. Gabrielides C., McCormack A.L., Hunt D.F., Christakos S.;Brain calbindin-D28k and an Mr 29,000 calcium binding protein in cerebellum are different but related proteins: evidence obtained from sequence analysis by tandem mass spectrometry.;Biochemistry 30:656-662(1991).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Calbindin,Calbindin D28,D-28K,Vitamin D-dependent calcium-binding protein,avian-type,CALB1,CAB27
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Conjugate / Tag	iFluor647
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	36 kDa
Calculated Molecular weight	30 kDa
Clonality	Polyclonal
Application Details	Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Mouse, Rat Immunoprecipitation, 0.5-2 μg/ml, Human
Gene Name	CALB1
Gene Full Name	Calbindin
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Calbindin is a calcium-binding protein belonging to the troponin C superfamily. Calretinin is expressed in central and peripheral nervous system and in many normal and pathological tissues. The rat and human calretinin exhibit 98% sequence homology and 91% homology to many other species. Two calcium binding proteins, calbindin and calretinin, have been reported to be expressed in abundance in Purkinje cells and other cell types in the cerebellum.
Immunogen	E.coli-derived human Calbindin recombinant protein (Position: A2-E175). Human Calbindin shares 99% amino acid (aa) sequence identity with both mouse and rat Calbindin.
Contents	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Calcium Binding Proteins, Calcium Signaling, Cell Type Marker, Neuron Marker, Neuroscience, Neurotransmission
Protein Name	Calbindin
Protein Function	Buffers cytosolic calcium. May stimulate a membrane Ca (2+)-ATPase and a 3', 5'-cyclic nucleotide phosphodiesterase.
Subcellular Localization	Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Localizes within both nucleus and cytoplasm of proliferative primary myoblasts and mostly within the nucleus of differentiated primary myoblasts. By virtue of the N-terminal PH domain, is recruited to sites of the plasma membrane containing increased PI (3, 4, 5)P3 or PI (3, 4)P2, cell membrane targeting is also facilitared by interaction with CLIP3.
Description	Boster Bio Anti-Calbindin/CALB1 Antibody Picoband® catalog # PB9045. Tested in IP, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Expressed in all cell types so far analyzed.
Sequence Similarities	Belongs to the calbindin family.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins

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BOS-PB9045-iFluor647-datasheet.pdf

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