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Anti-Bonzo/CXCR6 Antibody Picoband® Europäischer Partner

ArtNr BOS-PA2082
Hersteller Boster
Menge 100 ug/vial
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB, IHC
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Sensitivity >5000 cells
Citations 1. Kim, C. H., Kunkel, E. J., Boisvert, J., Johnston, B., Campbell, J. J., Genovese, M. C., Greenberg, H. B., Butcher, E. C. Bonzo/CXCR6 expression defines type 1-polarized T-cell subsets with extralymphoid tissue homing potential. J. Clin. Invest. 107: 595-601, 2001.
2. Liao, F., Alkhatib, G., Peden, K. W. C., Sharma, G., Berger, E. A., Farber, J. M. STRL33, a novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1. J. Exp. Med. 185: 2015-2023, 1997.
3. Matloubian, M., David, A., Engel, S., Ryan, J. E., Cyster, J. G. A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo. Nature Immun. 1: 298-304, 2000.

ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias C-X-C chemokine receptor type 6;CXC-R6;CXCR-6;CDw186;G-protein coupled receptor STRL33;G-protein coupled receptor bonzo;CD186;CXCR6;BONZO, STRL33, TYMSTR;
Similar products C X C chemokine receptor type 6 antibody, C-X-C chemokine receptor type 6 antibody, CD 186 antibody, CD186 antibody, CD186 antigen antibody, CDw186 antibody, Chemokine(C X C motif) receptor 6 antibody, Chemokine C X C motif receptor 6 antibody, Chemokine C-X-C Motif Receptor 6 antibody, Chemokine CXC motif receptor 6 antibody, Chemokine receptor 6 antibody, CXC chemokine receptor type 6 antibody, CXC R6 antibody, CXC-R6 antibody, CXCR 6 antibody, CXCR-6 antibody, CXCR6 antibody, CXCR6_HUMAN antibody, G protein coupled receptor antibody, G protein coupled receptor bonzo antibody, G protein coupled receptor STRL 33 antibody, G protein coupled receptor STRL33 antibody, G protein coupled receptor TYMSTR antibody, G-protein coupled receptor bonzo antibody, G-protein coupled receptor STRL33 antibody, STRL 33 antibody, STRL33 antibody, TYMSTR antibody
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
39 kDa
Calculated Molecular weight
39280 MW
Clonality
Polyclonal
Application Details
Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml, Human, By Heat
Western blot, 0.1-0.5?g/ml, Human
Manufacturer - Gene Name
CXCR6
Gene Full Name
C-X-C chemokine receptor type 6
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
CXCR6 (Chemokine, CXC Motif, Receptor 6), also known as STRL33, is a protein that in humans is encoded by the CXCR6 gene. By Southern blot analysis of genomic DNA and somatic cell hybrid analysis, Liao et al. (1997) mapped the single-copy STRL33 gene to chromosome 3. Matloubian et al. (2000) found that human and mouse cells expressing CXCR6 showed a strong chemotactic response to CXCL16 but not to other chemokines. The authors concluded that CXCL16 and CXCR6 probably function in interactions between dendritic cells and T cells and in regulating T-cell migration in the splenic red pulp. Kim et al. (2001) concluded that CXCR6 may be important in the trafficking of effector T cells mediating type-1 inflammation.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Bonzo, different from the related mouse and rat sequences by three amino acids.
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Antiviral Signaling, Host-Virus Interaction, Immune System Diseases, Immunology, Interspecies Interaction, Microbiology
Protein Name
C-X-C chemokine receptor type 6
Protein Function
Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.
Subcellular Localization
Cell membrane; Multi-pass membrane protein.
Description
Boster Bio Anti-Bonzo/CXCR6 Antibody catalog # PA2082. Tested in IHC, WB applications. This antibody reacts with Human.
Tissue Specificity
Expressed in lymphoid tissues and activated T cells.
Sequence Similarities
Belongs to the G-protein coupled receptor 1 family.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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